Paracoccidioidomycosis of the mouth: an emerging deep mycosis

Oslei Paes Almeida1, Jorge Jacks, Crispian Scully

  • 1Department of Oral Pathology, Dental School of Piracicaba-UNICAMP, Av. Limeira 901, CEP 13.414.903-CP 52, Piracicaba, SP, Brazil. oslei@fop.unicamp.br

Insights

Oral fungal infections, like Paracoccidioidomycosis, are increasingly recognized due to HIV/AIDS and global travel. This review focuses on oral manifestations relevant to dental science.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Oral Medicine

Context:

  • Oral fungal infections (mycoses) have gained prominence with the rise of Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS).
  • Increased global travel has led to greater exposure to tropical endemic infections.
  • Paracoccidioidomycosis, though rare globally, is endemic in Brazil and parts of Latin America, presenting significant health risks.

Purpose:

  • To review recent information on Paracoccidioidomycosis.
  • To emphasize aspects of Paracoccidioidomycosis particularly relevant to dental science.

Summary:

  • Paracoccidioidomycosis is a potentially life-threatening fungal infection common in specific Latin American regions.
  • It frequently manifests with oral lesions, making it a critical concern within oral medicine.
  • The review synthesizes current knowledge, highlighting implications for dental practitioners.

Impact:

  • Enhances understanding of a rare but severe oral mycosis.
  • Provides dental professionals with crucial information for diagnosing and managing Paracoccidioidomycosis.
  • Contributes to improved patient care for those affected by this infection.

Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...