Sleeping energy expenditure in paediatric patients with obstructive sleep apnoea syndrome
1Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, ROC.
Insights
Children with obstructive sleep apnoea syndrome (OSAS) showed a trend towards higher sleeping energy expenditure compared to healthy children. Further research into the metabolic impact of pediatric OSAS is needed.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Metabolic Research
Background:
- Obstructive sleep apnoea syndrome (OSAS) is a common condition in children.
- The metabolic consequences of pediatric OSAS, particularly during sleep, require further investigation.
Purpose of the Study:
- To investigate sleeping energy expenditure in children diagnosed with obstructive sleep apnoea syndrome.
- To compare sleeping energy expenditure between pediatric OSAS patients and matched controls.
Main Methods:
- Retrospective analysis of 24 children with OSAS and 23 controls.
- Sleeping energy expenditure measured using open-circuit indirect calorimetry during slow-wave sleep.
- Subjects were matched for age, sex, and ideal body weight.
Main Results:
- Mean sleeping energy expenditure was higher in the OSAS group (44.83 Kcal/day) compared to controls (40.71 Kcal/day).
- No significant association was found between OSAS severity and sleeping energy expenditure (r=0.34, P=0.27).
Conclusions:
- A trend suggests increased sleeping energy expenditure in children with obstructive sleep apnoea syndrome.
- Further research is warranted to explore the metabolic implications of pediatric OSAS.
Objective:
To investigate sleeping energy expenditure in paediatric patients with obstructive sleep apnoea syndrome.
Design:
Retrospective study. Setting. University teaching hospital, Hong Kong.
Patients And Methods:
A retrospective analysis comparing sleeping energy expenditure in patients with confirmed obstructive sleep apnoea syndrome and control subjects matched for age, sex, and ideal weight for body height. Subjects were recruited from the Paediatric Chest Clinic and all had undergone overnight polysomnography and sleeping energy expenditure measurement by open-circuit indirect calorimetry using a metabolic cart and canopy system. The measurements were taken during slow-wave sleep.
Results:
Twenty-four cases with obstructive sleep apnoea syndrome (apnoea hypopnoea index >5) and 23 control subjects were studied. Mean age and ideal weight for body height were 9.4 (standard deviation, 3.9) years and 152.5% (27.2%), respectively. Mean sleeping energy expenditure corrected for body weight for the cases and the control group were 44.83 (standard deviation, 10.49) Kcal/day and 40.71 (10.60) Kcal/day, respectively. Sleeping energy expenditure was not found to be associated with the severity of obstructive sleep apnoea syndrome (r=0.34, P=0.27).
Conclusion:
A trend towards greater sleeping energy expenditure was found in patients with obstructive sleep apnoea syndrome. Further studies on the metabolic aspects of this condition are required.
Related Concept Videos
01:21Sleep Apnea
The condition is more prevalent among...
01:26Respiratory Volumes and Capacities I
01:19Special considerations while measuring oxygen saturation
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is important.
01:24Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
01:20Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation: