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Updated: Aug 7, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Chronic kidney disease and cardiovascular disease in the Medicare population
Allan J Collins1, Shuling Li, David T Gilbertson
1United States Renal Data System, Minneapolis, Minnesota 55404, USA. acollins@usrds.org
Insights
Diabetes and chronic kidney disease (CKD) are increasing in Medicare patients, significantly raising the risk of death before end-stage renal disease (ESRD). Cardiovascular disease (CVD) is also prevalent and progresses rapidly in these patients.
Area of Science:
- Gerontology
- Nephrology
- Cardiology
Background:
- The prevalence and impact of diabetes, chronic kidney disease (CKD), and cardiovascular disease (CVD) on Medicare beneficiaries remain largely uncharacterized.
- The effect of these comorbidities on patient survival prior to end-stage renal disease (ESRD) is not well understood.
Purpose of the Study:
- To assess the prevalence of diabetes, CKD, and CVD in the Medicare population.
- To determine the impact of these conditions on patient survival before ESRD.
- To evaluate hospitalization rates and risk factor monitoring in affected patients.
Main Methods:
- Analysis of prevalent Medicare enrollees from 1996-2000.
- Assessment of diabetes, CKD, and CVD diagnoses.
- Evaluation of mortality versus ESRD probability, hospitalization rates, and specific testing (lipids, glycemic control) in diabetic patients.
Main Results:
- Diabetes prevalence in Medicare increased by 4.4% annually, reaching 18.9%.
- CKD affects approximately 726,000 elderly Medicare enrollees; those with CKD are 5-10 times more likely to die before ESRD.
- CVD is twice as common and progresses twice as fast in CKD patients, with high heart failure hospitalization rates. Risk factor monitoring for diabetes in CKD patients nearing ESRD is suboptimal.
Conclusions:
- Diabetes, the primary cause of ESRD, is rising in the Medicare population.
- CVD is highly prevalent, rapidly progressing, and associated with increased mortality before ESRD.
- There is a critical need for active identification and management of CKD patients, alongside improved risk factor monitoring.
Background:
The extent of diabetes, chronic kidney disease (CKD), and cardiovascular disease (CVD) in the Medicare population is relatively unknown. Also unknown is the effect of these diseases on patient survival before end-stage renal disease (ESRD).
Methods:
Prevalent cohorts of Medicare enrollees from 1996 to 2000 were assessed for diabetes and CKD, presence of CVD, and probability of death versus ESRD in the follow-up period. Hospitalization rates and, in diabetics, lipid testing and glycemic control monitoring were also assessed.
Results:
The prevalence of diabetes in the Medicare population increased at 4.4% per year, reaching 18.9% in the 1999-2000 cohort. Approximately 726,000 elderly Medicare enrollees carry a diagnosis code for CKD. Those with CKD are 5 to 10 times more likely to die before reaching ESRD than the non-CKD group. In CKD patients, CVD is twice as common and advances at twice the rate. Cardiovascular disease advances at a similarly higher rate in CKD patients who die and those who survive to ESRD. Heart failure hospitalizations are 5 times greater in CKD patients and only 30% less than those in dialysis patients. Only half of the CKD patients with diabetes who advance to ESRD had a lipid or glycosylated hemoglobin test done in the year before or after dialysis initiation.
Conclusion:
Diabetes, the leading cause of ESRD, is increasing in the general Medicare population at 4.4% per year. Cardiovascular disease is common, progresses at twice the rate, is associated with death before ESRD, and patients receive suboptimal risk factor monitoring. Active identification and treatment of CKD patients is needed.
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