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Related Experiment Videos

Exophiala oligosperma causing olecranon bursitis.

A D Bossler1, S S Richter, A J Chavez

  • 1Department of Pathology, University of Iowa Roy J.Lucille A. Carver College of Medicine, Iowa City, Iowa 52240, USA.

Journal of Clinical Microbiology
|October 9, 2003
PubMed
Summary

A rare fungal infection caused by Exophiala oligosperma was identified in a patient with Wegener's granulomatosis. Treatment involved aspiration and intrabursal amphotericin B, leading to successful recovery.

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Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Immunocompromised Hosts

Background:

  • Wegener's granulomatosis (now Granulomatosis with Polyangiitis) is a systemic vasculitis often treated with immunosuppressive therapy.
  • Chronic olecranon bursitis can be challenging to manage and may have infectious etiologies.
  • Immunosuppression increases the risk of opportunistic infections, including fungal infections.

Observation:

  • A 62-year-old male with a history of Wegener's granulomatosis and immunosuppressive therapy presented with chronic olecranon bursitis.
  • A black velvety mould was isolated from the olecranon bursa aspirate.
  • Microscopic examination revealed brown septate hyphae and tapered annellides, characteristic of an Exophiala species.

Findings:

  • Molecular identification using internal transcribed spacer rRNA sequencing confirmed the mould as Exophiala oligosperma.

Related Experiment Videos

  • This is a rare case of Exophiala oligosperma infection presenting as olecranon bursitis.

    • Implications:

    • Highlights the importance of considering fungal infections in immunocompromised patients with chronic bursitis.
    • Demonstrates the successful use of aspiration and intrabursal amphotericin B for treating Exophiala bursitis.
    • Suggests Exophiala species as potential pathogens in subcutaneous infections, particularly in susceptible individuals.