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Dissemination of extended-spectrum beta-lactamase-producing Enterobacteriaceae in pediatric intensive care units
Tsu-Lan Wu1, Ju-Hsin Chia, Lin-Hui Su
1Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Abstract:
To study the growing trend of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in pediatric intensive care units (PICUs), 88 nonrepetitive ESBL-producing isolates were prospectively collected and analyzed by molecular methods during a 16-month period. The emergence and dissemination of ESBL-producing Enterobacteriaceae in PICUs are the consequence of the clonal dissemination of a few epidemic strains along with the horizontal transmission of resistance gene-carrying plasmids among bacterial organisms.
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