A convenient method for the synthesis of 2-(beta-D-glycopyranosylthio) pyridines
Adel M E Attia1, Ashraf A El-Shehawy
1Department of Chemistry, Faculty of Education, University of Tanta (Kafr El-Sheikh Branch), Tanta, Egypt. adelmattia@hotmail.com
Nucleosides, Nucleotides & Nucleic Acids
|October 10, 2003
Abstract:
Treatment of piperidinium salts of dihydropyridinethiolates 3 with glycosyl bromides 4 in dry acetone provides a convenient and high yielding synthesis of 1,4-dihydro-3-cyanopyridine thioglycosides 5. The structures of 5 were confirmed by oxidation as well as by 1H NMR and 13C NMR spectral analysis.
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