[Interventional radiology, angioplasty and TIPS in Budd-Chiari syndrome]

O Núñez1, G de la Cruz, J Molina

  • 1Servicio de Aparato Digestivo. Hospital General Universitario Gregorio Marañón. Madrid. España.

Gastroenterologia Y Hepatologia
|October 10, 2003
PubMed

Insights

Transjugular intrahepatic portosystemic shunt (TIPS) and balloon angioplasty offer effective treatment for Budd-Chiari syndrome, improving patient outcomes and serving as alternatives to surgery.

Area of Science:

  • Interventional Radiology
  • Hepatology
  • Vascular Surgery

Background:

  • Budd-Chiari syndrome involves hepatic vein obstruction.
  • Surgical shunting is a traditional treatment.
  • Interventional radiology presents alternative therapeutic options.

Purpose of the Study:

  • To evaluate the efficacy of percutaneous balloon angioplasty and transjugular intrahepatic portosystemic shunt (TIPS) in Budd-Chiari syndrome treatment.
  • To compare these interventional techniques against surgical options.

Main Methods:

  • Retrospective analysis of 11 patients with Budd-Chiari syndrome.
  • Seven patients underwent either percutaneous balloon angioplasty (2) or TIPS (5).
  • Efficacy assessed by clinical improvement, ascites resolution, and Child-Pugh score changes.

Main Results:

  • Percutaneous balloon angioplasty yielded favorable outcomes with ascites resolution in two patients with isolated stenosis.
  • Transjugular intrahepatic portosystemic shunt (TIPS) resulted in clinical improvement and ascites resolution in four of five patients, with significant Child-Pugh score reduction.
  • One patient died post-TIPS, and two died from underlying disease during follow-up; no shunt malfunction was noted.

Conclusions:

  • Budd-Chiari syndrome management requires a multidisciplinary and individualized approach.
  • Transjugular intrahepatic portosystemic shunt (TIPS) is a viable decompressive option for medically refractory cases, serving as an alternative to surgical shunting.
  • Liver transplantation remains an option for patients unresponsive to interventional techniques.
Abstract

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