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Does angiographic severity of coronary artery disease predict postoperative outcome after coronary artery bypass
Fausto Biancari1, Jarmo Lahtinen, Esa Salmela
1Division of Cardiothoracic Surgery, Department of Surgery, University of Oulu and Oulu University Hospital, Oulu, Finland. faustobiancari@yahoo.it
Insights
The severity of coronary artery disease, assessed via angiography, impacts outcomes after coronary artery bypass surgery (CABG). Higher angiographic scores predict increased risk of death and low cardiac output syndrome post-CABG.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- Coronary artery disease (CAD) severity assessment is crucial for surgical planning.
- The impact of angiographic findings on immediate outcomes following coronary artery bypass surgery (CABG) remains unclear.
Purpose of the Study:
- To investigate the relationship between coronary artery disease severity, evaluated through angiography, and postoperative outcomes in patients undergoing isolated on-pump CABG.
Main Methods:
- A cohort of 2,233 patients undergoing isolated on-pump CABG was analyzed.
- Coronary angiographic status of 15 coronary arteries/segments was graded based on stenosis severity, occlusion, or non-visualization.
- Multivariate analysis was employed to assess the predictive value of the overall coronary angiographic score and specific vessel statuses on postoperative outcomes.
Main Results:
- In-hospital mortality was 1.7% (37 patients), and low cardiac output syndrome occurred in 4.8% (108 patients).
- The overall coronary angiographic score significantly predicted postoperative death (p=0.03) and low cardiac output syndrome (p=0.04).
- Adverse outcomes were most strongly associated with the status of the proximal left circumflex coronary artery, diagonal arteries, and left obtuse marginal arteries.
Conclusions:
- Coronary artery disease severity, as determined by angiography, significantly influences immediate postoperative outcomes after CABG.
- Angiographic assessment provides valuable prognostic information for patients undergoing coronary artery bypass surgery.
Objective:
It is not clear whether the severity of coronary artery disease as assessed on angiography has an impact on the postoperative outcome after coronary artery bypass surgery (CABG).
Design:
The angiographic status of 15 coronary arteries/segments of 2,233 patients who underwent isolated on-pump CABG was graded according to the following criteria: 1 = no stenosis; 2 = stenosis <50%; 3 = stenosis of 50-69%; 4 = stenosis of 70-89%; 5 = stenosis of 90-99%; 6 = vessel occlusion; and 7 = vessel is not visualized.
Results:
Thirty-seven patients (1.7%) died during the in-hospital stay and 108 (4.8%) developed postoperatively low cardiac output syndrome. Multivariate analysis showed that along with other risk factors the overall coronary angiographic score was predictive of postoperative death (p = 0.03; OR: 1.027, 95% CI: 1.003-1.052) and of low cardiac output syndrome (p = 0.04; OR: 1.172, 95% CI: 1.010-1.218). The status of the proximal segment of the left circumflex coronary artery, the diagonal arteries and the left obtuse marginal arteries was most closely associated with adverse postoperative outcome.
Conclusion:
The angiographic status of coronary arteries has an impact on the immediate outcome after CABG.
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