Related Experiment Video
Updated: Aug 30, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
The aging spine: new technologies and therapeutics for the osteoporotic spine
Joseph M Lane1, Michael J Gardner, Julie T Lin
1Metabolic Bone Disease Service, Hospital for Special Surgery, New York, New York, USA. lanej@hss.edu
Abstract:
Osteoporosis results in low-energy fractures of the spine. The load necessary to cause a vertebral fracture is determined by the characteristics related to the vertebral body structure, mineral content, and quality of bone. Radiographic techniques centered on dual X-ray absorptiometry (DXA) permit a determination of bone mass and fracture risk. Current medical therapies principally using bisphosphonate and pulsatile PTH profoundly decrease the risk of fracture (50+%). Fall prevention strategies can further decrease the possibility of fracture. A comprehensive approach to osteoporosis can favorably alter the disease.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Degenerative Disc Disease I: Introduction
Osteoclasts in Bone Remodeling
Bone Remodeling and Repair