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Updated: Aug 30, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Use of contrast enhancement for the assessment of left ventricular function

Victor Mor-Avi1, Roberto M Lang

  • 1Noninvasive Cardiac Imaging Laboratories, Department of Medicine, University of Chicago Medical Center, Chicago 60637, Illinois, USA. vmoravi@medicine.bsd.uchicago.edu

Echocardiography (Mount Kisco, N.Y.)
|October 11, 2003
PubMed

Insights

Improving echocardiography contrast agents enhances endocardial visualization for better assessment of left ventricular (LV) function and coronary artery disease detection. This leads to more accurate evaluations of cardiac performance.

Area of Science:

  • Cardiovascular imaging
  • Echocardiography
  • Cardiac function assessment

Background:

  • Accurate endocardial visualization is crucial for diagnosing coronary artery disease and assessing left ventricular (LV) ejection fraction.
  • Poor echocardiographic image quality often hinders consistent endocardial boundary detection throughout the cardiac cycle.
  • Current limitations impact the objective evaluation of global and regional LV function.

Purpose of the Study:

  • To review recent advancements in contrast echocardiography for evaluating LV function.
  • To highlight new quantitative approaches for assessing LV performance.
  • To discuss the potential impact of these developments on clinical practice.

Main Methods:

  • Review of recent literature on contrast echocardiography techniques.
  • Discussion of novel quantitative methods for LV function assessment.
  • Exploration of technological improvements in echocardiographic imaging.

Main Results:

  • New objective, quantitative approaches have been developed to improve LV function assessment.
  • Contrast agents show promise in enhancing endocardial visualization.
  • These advancements may lead to more accurate and reproducible evaluations of LV performance.

Conclusions:

  • Enhanced endocardial visualization through improved echocardiography, particularly with contrast agents, is key.
  • Objective, quantitative methods are emerging for LV function assessment.
  • Further integration of these developments could significantly improve the clinical evaluation of cardiac function.

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