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Updated: Aug 30, 2026

Design of Solid-State Fermentation Systems for Polymer Hydrolytic Extracellular Enzyme Production by Filamentous Fungi
Published on: June 6, 2025
Solid state fermentation reactors: from lab scale to pilot plant
A Durand1, R Renaud, S Almanza
1Plate-forme de Prédéveloppement en Biotechnologie, Institut National de la Recherche Agronomique (INRA), Dijon, France.
Abstract:
Relatively many workers in the world are studying different aspects in SSF processes but few are working on reactor design and scale-up. From about 10 years, we are developing reactors from lab scale to pilot plant, based on the same technology, reactor design and flowsheet to allow fermentation with a deep layer (up to 1 m in the pilot plant). These reactors have all a forced aeration and the possibility or not to agitate. Regulations of temperature and water content of the culture are monitored by a special device.
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