Influenza in children: the German perspective
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Published on: September 7, 2017
1Department of Pediatrics, St Josefs Hospital, Freiburg, Germany. johannes.forster@rkk-sjk.de
Insights
Influenza poses a significant health risk to children, with approximately 120 annual hospitalizations per 100,000 children. Premature infants and those with chronic conditions face higher risks from this common respiratory illness.
Area of Science:
- Pediatric Infectious Diseases
- Epidemiology
- Public Health
Background:
- Influenza is a significant pediatric illness, yet comprehensive epidemiologic data in children remain limited.
- Understanding influenza's impact on children is crucial for public health initiatives.
Purpose of the Study:
- To analyze the epidemiology of influenza in infants and children using German data.
- To determine influenza-associated hospitalization rates and risk factors in pediatric populations.
Main Methods:
- Analysis of German epidemiologic data from three distinct studies: PRIDE, PID-ARI-net, and a sentinel surveillance study.
- Inclusion of data from population-based, hospital-based, and sentinel surveillance sources for comprehensive analysis.
Main Results:
- Influenza-associated hospitalization rates were approximately 120 per 100,000 children (aged 0-5 years).
- Premature infants and children with cardiac or pulmonary conditions had increased hospitalization risks.
- Outpatient consultation rates for influenza-related lower respiratory tract illness were 1.1 per 100 children annually.
Conclusions:
- Influenza represents a substantial health hazard for all children, necessitating targeted prevention and management strategies.
- Epidemiologic evidence confirms the significant burden of influenza on pediatric health.
Background:
Influenza is recognized as an important disease in infants and children, but epidemiologic data on influenza in children are limited.
Methods:
We analyzed German epidemiologic data from three sources: a population-based study in children 0 to 3 years of age [Paediatric Respiratory Infection in Germany (PRIDE) study]; a multicenter hospital-based survey of children 0 to 16 years of age (www.pid-ari.net); and a sentinel study (Deutsche Arbeitsgemeinschaft Influenza) comparing influenza activity and numbers of consultations for respiratory infections in children and adults.
Results:
In 1996 to 2001, the PID-ARI-net and the PRIDE studies showed that the rate of influenza-associated hospitalizations was approximately 120/100 000 children (0 to 5 and 0 to 3 years of age, respectively). Children born prematurely and those with underlying cardiac or pulmonary disease were at increased risk of hospitalization. The mean duration of hospital stay was 6.3 days, which is equal to the mean length of hospitalization for respiratory syncytial virus infections in continental Europe. Few nosocomial infections were reported. The outpatient consultation rate per year for lower respiratory tract illness caused by influenza virus was 1.1/100 children.
Conclusion:
Direct and indirect epidemiologic evidence indicates that influenza is a significant health hazard for all children.
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