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A primary retroperitoneal serous cystadenocarcinoma with clinically aggressive behavior
Archives of Gynecology and Obstetrics
|October 11, 2003
Summary
This case report details a rare primary retroperitoneal serous cystadenocarcinoma in a 44-year-old woman. The study highlights the aggressive clinical behavior of this uncommon ovarian-type cancer.
Area of Science:
- Gynecologic Oncology
- Surgical Pathology
- Medical Imaging
Background:
- Primary retroperitoneal serous cystadenocarcinoma is an exceptionally rare malignancy.
- This report presents the fourth documented case in the world literature.
Observation:
- A 44-year-old woman presented with a left retroperitoneal mass.
- Imaging revealed a complex mass with enhanced mural nodules and septa.
- Elevated serum cancer antigen 19-9 (CA19-9) levels were noted.
Findings:
- Pathological examination confirmed a well-differentiated papillary serous cystadenocarcinoma of ovarian type with lymph node metastases.
- The patient experienced pelvic recurrence and subsequent liver metastasis.
- Tumor markers CA19-9 and cancer antigen 125 (CA125) significantly increased post-operatively.
Implications:
- Primary retroperitoneal serous cystadenocarcinoma exhibits aggressive clinical behavior.
- Multidisciplinary management including surgery and chemotherapy (docetaxel and carboplatin) is indicated.
- This case underscores the importance of considering rare malignancies in retroperitoneal masses.
