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Updated: Aug 30, 2026

Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo
Published on: September 26, 2016
PRESS-based proton single-voxel spectroscopy and spectroscopic imaging with very short echo times using asymmetric RF
Christian Geppert1, Wolfgang Dreher, Dieter Leibfritz
1Fachbereich 2 (Chemie), Universität Bremen, Leobener Strasse, 28334 Bremen, Germany.
Abstract:
Modified point-resolved spectroscopy (PRESS) sequences for single voxel spectroscopy (MRS) and spectroscopic imaging (SI) with very short echo time ( T(E)) are described using asymmetric radio-frequency (RF) pulses as well as an optimized design and timing of the PRESS sequence. The proposed sequences were implemented on a standard 4.7 T imaging system yielding a T(E) of 6.0 ms only. Simulations and experimental data measured on phantoms and the rat brain in vivo are presented for MRS and SI showing a high signal-to-noise ratio and hardly any phase distortions caused by J-coupling.
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