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Published on: May 30, 2013

Measles in children with HIV infection: report of five cases

Vania De Carvalho1, Leide Parolin Marinoni, Luzilma Flenick Martins

  • 1Pediatric Dermatology Division, Pathology Department, Clinical Hospital, Federal University of Paraná, Curitiba, PR, Brazil. rcarvalho50@hotmail.com

The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases
|October 14, 2003
PubMed

Insights

Children with human immunodeficiency virus (HIV) infection experienced measles during an outbreak. Antiretroviral therapy may reduce measles severity in pediatric patients with acquired immunodeficiency syndrome (AIDS).

Area of Science:

  • Pediatric Infectious Diseases
  • Immunology

Background:

  • Patients with acquired immunodeficiency syndrome (AIDS) often develop skin issues due to weakened immune systems and malnutrition.
  • The presentation and severity of skin lesions can vary significantly in individuals with AIDS.

Observation:

  • A prospective study examined five children with human immunodeficiency virus (HIV) infection during a measles outbreak.
  • Observed both typical and atypical measles presentations, including one case with negative serology.
  • Pulmonary complications were noted in some patients, but no fatalities occurred.

Findings:

  • Measles presented with varied clinical manifestations in pediatric patients with HIV infection.
  • The absence of mortality suggests a potential protective effect of ongoing antiretroviral treatment.

Implications:

  • Antiretroviral therapy might mitigate measles morbidity in children with HIV.
  • Further research is warranted to understand the interaction between HIV, measles, and antiretroviral treatments in pediatric populations.

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