Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary nonphylloides breast sarcomas.

D Kay Blanchard1, Carol A Reynolds, Clive S Grant

  • 1Department of Surgery, Mayo W-6, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.

American Journal of Surgery
|October 14, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Papillary Thyroid Carcinoma (PTC) in Children and Adults: Comparison of Initial Presentation and Long-Term Postoperative Outcome in 4432 Patients Consecutively Treated at the Mayo Clinic During Eight Decades (1936-2015).

World journal of surgery·2017
Same author

FHIT and TSG101 in thyroid tumours: aberrant transcripts reflect rare abnormal RNA processing events of uncertain pathogenetic or clinical significance.

Clinical endocrinology·2017
Same author

Selective Arterial Calcium Stimulation With Hepatic Venous Sampling Differentiates Insulinoma From Nesidioblastosis.

The Journal of clinical endocrinology and metabolism·2015
Same author

AACE/ACE disease state clinical review: pancreatic neuroendocrine incidentalomas.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2015
Same author

Abstract 99: reducing unplanned reoperations for mastectomy skin flap necrosis - a multidisciplinary approach.

Plastic and reconstructive surgery·2015
Same author

Impact of variant pancreatic arterial anatomy and overlap in regional perfusion on the interpretation of selective arterial calcium stimulation with hepatic venous sampling for preoperative localization of occult insulinoma.

Surgery·2015
Same journal

Women with firearm injuries: A multicenter mixed-methods study.

American journal of surgery·2026
Same journal

SBAS presidential address: A surgeon-scientist's journey from haptic science to digital performance metrics.

American journal of surgery·2026
Same journal

Using Dr. Google and AI to stay informed.

American journal of surgery·2026
Same journal

Revealing the sex divide: Primary hyperparathyroidism across the American population.

American journal of surgery·2026
Same journal

Pressure points: A pilot study using the NASA-TLX tool to measure the intensity of Acute care surgery work.

American journal of surgery·2026
Same journal

Raised to run faster, not to heal moral injury and the surgeon's capacity to lead.

American journal of surgery·2026
See all related articles

Primary breast sarcoma is rare, with poor prognosis and high recurrence rates. Surgical removal is the only effective treatment, as adjuvant therapies did not improve survival in this study.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Medical Oncology

Background:

  • Primary breast sarcoma is a rare malignancy, accounting for less than 1% of all breast cancers.
  • Understanding the clinical behavior of these rare tumors is crucial for effective patient management.

Purpose of the Study:

  • To investigate the clinical presentation of primary breast sarcoma.
  • To analyze treatment strategies and patient outcomes for primary breast sarcoma.
  • To evaluate the prognostic factors influencing survival in breast sarcoma patients.

Main Methods:

  • Retrospective review of patients diagnosed with primary breast sarcoma at Mayo Clinic between 1975 and 2001.
  • Data collection included patient demographics, tumor characteristics, treatment modalities, and follow-up information.

Related Experiment Videos

  • Statistical analysis was performed to assess survival rates and recurrence patterns.

    • Main Results:

    • The study included 55 patients with various sarcoma subtypes, including angiosarcoma, malignant fibrous histiocytoma, and stromal sarcoma.
    • High rates of recurrence (55%) and mortality (43%) were observed.
    • Angiosarcoma cases showed a significantly poorer prognosis compared to other sarcoma types.
    • Adjuvant chemotherapy and radiation therapy did not demonstrate a survival benefit.

    Conclusions:

    • Primary non-phylloides breast sarcomas are rare and associated with poor treatment outcomes.
    • Surgical extirpation is currently the primary effective treatment modality.
    • Further research is needed to identify more effective adjuvant therapies for breast sarcoma.