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Does ultrasound core breast biopsy predict histologic finding on excisional biopsy?
Joseph P Crowe1, Rebecca J Patrick, Lisa A Rybicki
1Cleveland Clinic Breast Center, Cleveland Clinic Foundation, 9500 Euclid Ave, A10, Cleveland, OH 44195, USA.
Background:
The purpose of this study was to determine whether ultrasound-guided core breast biopsy accurately predicts the histologic finding of a subsequent excisional procedure.
Methods:
Data were collected prospectively from 1997 to 2001 for 832 ultrasound-guided core breast biopsies (USB) that were followed by excisional breast procedure (EP) within 1 year at our institution. The principal histologic finding obtained at USB and EP was identified for each procedure and the degree of agreement was assessed.
Results:
The USB histology predicted EP histology in 90% (n = 746) of the procedures. The USB histology was more significant than EP histology in 3% (n = 22) of procedures; USB histology underdetermined EP histology in 7% (n = 64) of procedures. Overall, our results indicate moderate agreement between the principal histology identified at USB relative to that identified at EP.
Conclusions:
Ultrasound-guided core breast biopsy is an effective diagnostic method, but sampling limitations do exist.