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Current trends in modern pharmaceutical analysis for drug discovery
Hwee-Ling Koh1, Wai-Ping Yau, Pei-Shi Ong
1Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, 117543, Singapore. phakohhl@nus.edu.sg
Drug Discovery Today
|October 14, 2003
Summary
Modern pharmaceutical analysis uses advanced techniques like nanotechnology and high-throughput screening throughout drug discovery. These innovations accelerate the search for new medicines to treat human diseases.
Area of Science:
- Analytical Chemistry
- Pharmaceutical Sciences
- Drug Discovery
Background:
- Pharmaceutical analysis traditionally focused on chemical analysis of drug molecules.
- Modern pharmaceutical analysis has expanded to include advanced techniques and applications.
- Analytical advancements are crucial for the entire drug discovery pipeline.
Purpose of the Study:
- To review the application of modern analytical technologies in drug discovery.
- To highlight how evolving analytical methods impact the search for new therapeutics.
- To provide an overview of current trends in pharmaceutical analysis for drug development.
Main Methods:
- Review of current literature on pharmaceutical analysis and drug discovery.
- Analysis of emerging technologies such as chemometrics, microdosing, and nanotechnology.
- Examination of high-throughput technologies and miniaturization in analytical processes.
Main Results:
- Advanced analytical techniques are integral to all phases of drug discovery.
- Combination techniques and high-throughput methods enhance efficiency and scope.
- Nanotechnology and microdosing offer novel approaches to drug analysis and development.
Conclusions:
- Evolving analytical technologies are critical for advancing drug discovery.
- Continued innovation in pharmaceutical analysis drives the development of new treatments.
- The integration of diverse analytical strategies accelerates the search for novel therapeutics.