Related Experiment Videos
[Left ventricular functional parameters using ECG-gated multidetector spiral CT in comparison with invasive
M Heuschmid1, A Küttner, S Schröder
1Abteilung für Radiologische Diagnostik, Universitätsklinik Tübingen. martin.heuschmid@med.uni-tuebingen.de
Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|October 14, 2003
Summary
Multidetector CT (MDCT) with retrospective ECG-gating accurately estimates left ventricular function, showing good correlation for end-systolic volume and ejection fraction compared to ventriculography. However, MDCT tends to overestimate volumes and underestimate ejection fraction.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Assessing left ventricular function is crucial for diagnosing and managing cardiac diseases.
- Conventional ventriculography is invasive and carries risks.
- Multidetector CT (MDCT) offers a non-invasive imaging modality for cardiac assessment.
Purpose of the Study:
- To evaluate the accuracy of left ventricular function assessment using MDCT with retrospective ECG-gating.
- To compare MDCT-derived functional parameters with those obtained from conventional ventriculography.
Main Methods:
- 26 patients underwent retrospectively ECG-gated MDCT and conventional coronary angiography with ventriculography.
- Cardiac CT data were reconstructed in end-systolic and end-diastolic phases.
- End-systolic volume (ESV), end-diastolic volume (EDV), and ejection fraction (EF) were calculated and compared.
Main Results:
- MDCT achieved sufficient image quality in all cases.
- MDCT showed good correlation with ventriculography for ESV (r=0.81) and EF (r=0.79).
- MDCT tended to significantly overestimate EDV (p=0.008) and ESV (p=0.003), and underestimate EF (p=0.001).
Conclusions:
- Retrospective ECG-gated MDCT provides efficient estimation of left ventricular function.
- MDCT offers valuable non-invasive cardiac imaging information.
- Significant overestimation of volumes and underestimation of EF by MDCT compared to ventriculography warrant consideration.