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Transverse myelitis associated with Acinetobacter baumanii intrathecal pump catheter-related infection

Eroboghene E Ubogu1, Judah R Lindenberg, Mary Ann Werz

  • 1Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Abstract

Insights

Transverse myelitis is a rare complication after intrathecal pump placement for pain. Early diagnosis and treatment, including pump removal and antibiotics, can lead to recovery.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Neurosurgery

Background:

  • Intrathecal pump implantation is a treatment for chronic pain.
  • Late neurologic complications can arise after intrathecal pump placement.

Observation:

  • A 32-year-old patient developed progressive lower extremity numbness and weakness 2 months post-intrathecal pump implantation.
  • Symptoms included sensory loss, motor deficits, and bowel/bladder incontinence, indicative of myelopathy.
  • Magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) analysis confirmed transverse myelitis.

Findings:

  • A catheter-tip infection with Acinetobacter baumanii was identified.
  • Removal of the intrathecal pump and treatment with intravenous corticosteroids and antibiotics led to significant clinical improvement within 30 days.

Implications:

  • Transverse myelitis should be considered a potential late complication of intrathecal pump placement.
  • Prompt medical intervention, including pump removal, is crucial to prevent irreversible spinal cord damage.
  • Early treatment can support favorable patient recovery outcomes.

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