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Sequence analysis of the ROB-1 beta-lactamase gene from Actinobacillus pleuropneumoniae
1Diagnostic Laboratory, NYS College of Veterinary Medicine, Cornell University, Ithaca 14853.
Veterinary Microbiology
|October 1, 1992
Abstract:
The ROB-1 beta-lactamase gene from Actinobacillus pleuropneumoniae was cloned and sequenced. The structural gene encodes a 305 amino acid polypeptide. The ROB-1 beta-lactamase gene sequence is identical to that derived from Pasteurella haemolytica and only one amino acid different from that of Haemophilus influenzae, suggesting that they are derived from the same ancestor, and transformed from one to another.