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Updated: Aug 30, 2026

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Published on: January 31, 2020
Pre-exposure chemoprophylaxis (PREP) as an HIV prevention strategy
1Royal Free Centre for HIV Medicine, Royal Free Hospital, Pond Street, London NW3 2QG. myoule@rfh1.demon.co.uk
Abstract:
Chemoprophylaxis may be a prevention strategy for the sexual transmission of human immunodeficiency virus (HIV). Evidence suggests that condom use has waned with the availability of antiretroviral medication, at least in some resource-rich settings. Barrier methods of HIV prevention have inherent problems, and the potential for failure. Microbicide research has focused primarily on male-to-female transmission. Analogous to post-exposure prophylaxis, HIV prevention may be achieved by pre-exposure prophylaxis in some settings. Research in this potential strategy may be rewarding.
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