[Endothelial dysfunction in patients with chronic colitis]

The work shows that patients with chronic colitis have an expressed endothelial dysfunction, which becomes apparent as an increase of the level of vasoconstrictor endothelin-1 and decrease of the level of vasodilator nitric oxide. The obtained data indicate the role of the endothelial dysfunction in the pathogenesis of chronic colitis. The efficiency of the complex therapy with the use of folic acid and zinkteral for the restoration of the endothelium function is marked in comparison with the group of the patients treated with the help of the basic therapy.