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Polymorphonuclear proteolytic activity and milk composition change.

Yves Le Roux1, François Laurent, Fatima Moussaoui

  • 1Laboratory of Animal Science, National Polytechnic Institute of Lorraine, ENSAIA-INRA, 2, avenue de la Forêt de Haye, 54505 Vandoeuvre-lès-Nancy Cedex, France. yves.leroux@ensaia.inpl-nancy.fr

Veterinary Research
|October 15, 2003
PubMed
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Increased Quarter Milk Cell Count (QMCC) and Tank Milk Cell Count (TMCC) negatively impact milk quality by altering biochemical and technological parameters. Somatic cells, particularly neutrophils (PMN), play a significant role in caseinolysis during udder inflammation.

Area of Science:

  • Dairy Science
  • Animal Health
  • Biochemistry

Background:

  • Somatic cell counts (SCC) like Quarter Milk Cell Count (QMCC) and Tank Milk Cell Count (TMCC) are key indicators of udder health.
  • Elevated SCC are associated with changes in milk composition and processing quality.

Purpose of the Study:

  • To investigate the relationship between QMCC and TMCC and milk's biochemical and technological properties.
  • To elucidate the mechanisms by which somatic cells influence milk quality during udder inflammation.

Main Methods:

  • Analysis of milk biochemical and technological parameters in relation to QMCC and TMCC.
  • Evaluation of the impact of somatic cells, especially neutrophils (PMN), on milk caseinolysis.

Main Results:

Related Experiment Videos

  • All measured milk parameters were affected by increasing TMCC and QMCC up to 600,000 cells/mL.
  • Udder inflammation involves decreased synthesis, altered milk barrier permeability, and increased proteolytic activities.
  • Specific proteolytic activities of PMN contribute significantly to caseinolysis.

Conclusions:

  • Somatic cells, particularly PMN, play a crucial role in modifying milk quality through proteolytic actions.
  • Understanding these mechanisms is vital for managing milk quality and dairy product processing.
  • The study proposes hypothetical mechanisms for PMN-induced caseinolysis and discusses the interplay of plasmin, bacteria, and somatic cells.