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The evolution of a resistant pathogen--the case of MRSA
1Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK. m.c.enright@bath.ac.uk
Current Opinion in Pharmacology
|October 16, 2003
Abstract:
Recent advances in molecular epidemiological methods have elucidated the evolutionary pathways by which modern methicillin-resistant Staphylococcus aureus have evolved. Only five major lineages of hospital methicillin-resistant Staphylococcus aureus exist, but these are globally distributed and evolving resistance to even the newest antibiotics.