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Published on: June 5, 2021
[Detection and analysis of SARS coronavirus-specific antibodies in sera from non-SARS children]
Lin-hai Li1, Yu-ling Shi, Ping Li
1Department of Clinical Laboratory, Guangzhou General Hospital of Guangzhou Command, Guangzhou 510010, China. linhaili@hotmail.com
Objective:
To examine the presence of severe acute respiratory syndrome (SARS) coronavirus-specific antibodies in the sera from non-SARS children.
Methods:
Indirect immunofluorescent assay and double-antigen sandwich enzyme-linked immunosorbent assay (ELISA) were used to detect the virus-specific antibodies in sera of 1,060 non-SARS children in Guangzhou.
Results:
All the serum samples from the 1,060 non-SARS children were negative for both IgG and IgM antibodies against SARS coronavirus as determined by indirect immunofluorescent assay, with only two serum samples showing weak positivity for SARS coronavirus-specific antibodies identified by double-antigen sandwich ELISA.
Conclusion:
No SARS coronavirus-specific antibody are present in the sera of non-SARS children.
