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Published on: February 26, 2013
Factors determining long-term maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation
Dariusz Kosior1, Marian Szulc, Radosław Piatkowski
1Chair and Department of Cardiology, Medical University of Warsaw, Poland.
Insights
Maintaining sinus rhythm after atrial fibrillation cardioversion is possible. Smaller left atrial area and increased left ventricular fractional shortening predict successful long-term sinus rhythm maintenance.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Imaging
Background:
- Maintaining sinus rhythm (SR) after cardioversion (CV) for persistent atrial fibrillation (AF) reduces stroke risk and anticoagulation complications.
- Identifying predictors for SR maintenance is crucial for patient management.
Purpose of the Study:
- To identify clinical and echocardiographic predictors of maintaining SR for one year post-CV in persistent AF patients.
- To compare echocardiographic parameters between patients who maintained SR and those with AF recurrence.
Main Methods:
- A randomized controlled trial involving 104 patients with persistent AF undergoing CV.
- Transthoracic echocardiography performed before CV.
- Linear and logistic regression analysis to compare echocardiographic data and predict SR maintenance over 12 months.
Main Results:
- Sinus rhythm was maintained in 63.5% of patients at one-year follow-up.
- A smaller left atrial area (<28 cm²) was significantly associated with SR maintenance (p<0.02; RR 1.72).
- Increased left ventricular fractional shortening (25-40%) also predicted SR maintenance (p<0.05; RR 1.2).
Conclusions:
- Left atrial area and left ventricular fractional shortening are independent predictors of SR maintenance after successful CV in persistent AF.
- These echocardiographic parameters can aid in stratifying patients likely to maintain SR.
Background:
Long-term maintenance of sinus rhythm (SR) after successful cardioversion (CV) of persistent atrial fibrillation (AF) carries a low risk of stroke and may avoid the risks associated with anticoagulation.
Aim:
To determine the clinical and echocardiographic predictors of maintaining SR during one-year follow-up.
Methods:
The initial study group consisted of 205 patients with persistent AF of whom 104 (33 females, 71 males, mean age 60.4+/-7.4 years) were randomised to SR restoration and maintenance. The results of transthoracic echocardiography, obtained before CV, were compared between patients who remained in SR and those in whom AF recurred during a one-year follow-up period, using the linear and logistic regression analysis.
Results:
SR was present in 63.5% of patients at the end of the follow-up period. Of several analysed echocardiographic parameters, an increased left atrial area (<28 cm(2)) (p<0.02; RR 1.72, OR 1.09-2.71) and an increase in the fractional shortening of the left ventricle (range 25-40%, p<0.05, RR 1.2, OR 1.01-1.44) were significantly associated with SR maintenance during a 12-month follow-up period.
Conclusions:
Left atrial area and left ventricular fractional shortening are the independent predictors of the maintenance of SR after successful CV in patients with persistent AF.
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