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Published on: November 4, 2010
[Guideline 'Treating asthma in children' for pediatric pulmonologists (2nd revised edition). I. Diagnosis and
E J Duiverman1, Q Jöbsis, E E van Essen-Zandvliet
1Academisch Ziekenhuis, Beatrix Kinderkliniek, afd. Kindergeneeskunde, sectie Kinderlongziekten, Postbus 30.001, 9700 RB Groningen. e.j.duiverman@bkk.azg.nl
Insights
Accurate asthma diagnosis relies on case history and physical exams, especially in young children where symptom progression is key. Avoid routine tests; consider allergy testing for those under 4 and lung function tests from age 5.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
Background:
- Asthma diagnosis in infants and preschool children presents challenges, necessitating a focus on symptom progression over time.
- Routine laboratory and radiological investigations are generally not recommended for diagnosing asthma in this age group.
Discussion:
- Allergy testing can be beneficial for children under 4 years old.
- Lung function investigations are suitable for children aged 5-6 years and older.
- Fraction of exhaled nitric oxide (FeNO) offers a non-invasive method to assess bronchial inflammation.
Key Insights:
- Clinical assessment, including case history and physical examination, remains foundational for asthma diagnosis.
- Age-appropriate diagnostic tools, such as allergy testing and lung function tests, should be selectively employed.
- Non-invasive biomarkers like FeNO can aid in evaluating airway inflammation.
Outlook:
- Preventive strategies include house dust mite reduction for sensitized individuals.
- Breastfeeding for the first 4-6 months may offer a preventive measure for high-risk infants.
- Further research into early asthma prediction and prevention in at-risk populations is warranted.
Abstract:
The case history and physical examination form the corner-stones for asthma diagnosis. Establishing the correct diagnosis may be difficult in infants and preschool children; in such cases the progression of the symptoms over time is important. Routine laboratory and radiological investigations are advised against. Allergy testing may be useful in children under the age of 4 years. Lung function investigations can be used from the age of 5 to 6 years onwards. Non-invasive investigations into the degree of bronchial inflammation can be performed by measuring the fraction nitric oxide in exhaled air. House dust mite reduction is a useful measure for preventing asthma if sensitisation has been demonstrated. Breast-feeding during the first 4 to 6 months of life can be considered as a preventive measure in infants with an increased risk of developing asthma and allergy.
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