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The development and preliminary validation of a Preference-Based Stroke Index (PBSI)
Lise Poissant1, Nancy E Mayo, Sharon Wood-Dauphinee
1McGill University, Health Informatics Research Group, 1140 Pine Ave West, Montreal, Quebec, H3A 1A3, Canada. lise.poissant@mcgill.ca
Health and Quality of Life Outcomes
|October 17, 2003
Summary
A new stroke-specific health index, the Preference-based Stroke Index (PBSI), was developed to measure health-related quality of life (HRQL) in stroke patients for clinical and economic studies.
Area of Science:
- Health Economics
- Rehabilitation Medicine
- Psychometrics
Background:
- Health-related quality of life (HRQL) is crucial in stroke recovery but difficult to quantify for economic analyses.
- Existing preference-based HRQL measures do not adequately address stroke-specific outcomes.
- There is a need for a stroke-specific tool to assess HRQL in clinical and economic evaluations.
Purpose of the Study:
- To develop the first stroke-specific health index, the Preference-based Stroke Index (PBSI).
- To create a comprehensive measure for HRQL in stroke patients suitable for cost-effectiveness studies.
Main Methods:
- The PBSI comprises 10 items (e.g., walking, memory, self-esteem) with a 3-point response scale.
- Items were selected based on their known impact from stroke.
- Scaling properties and preference-weights from stroke survivors and caregivers were used to create a cumulative score.
Main Results:
- The PBSI demonstrated no ceiling effect in high-functioning stroke survivors, unlike the EQ-5D.
- Significant correlations were observed between the PBSI and SF-36 scales for physical function, vitality, and social functioning.
- The PBSI effectively differentiated stroke patients by severity and functional independence.
Conclusions:
- The PBSI shows promising content validity and preliminary construct validity.
- Further research is required to develop a multiattribute utility function and fully establish its psychometric properties.