Related Experiment Video
Updated: Aug 18, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
A biopsychosocial approach to premenstrual dysphoric disorder
1Women's Health Concerns Clinic and Father Sean O'Sullivan Research Centre, St. Joseph's Healthcare, Fontbonne Building, 6th Floor, 50 Charlton Avenue East, Hamilton, Ontario L8N 4A6, Canada.
Abstract:
Though epidemiological data is difficult to collect, existing evidence indicates that there is a small but significant population of women in whom premenstrual symptoms, and particularly affective symptoms, severely impair functioning. Although PMDD is predominantly regarded as a biologically based illness, there is strong evidence that variables such as life stress, history of sexual abuse, and cultural socialization are important determinants of premenstrual symptoms. In diagnosing and treating PMDD patients, attention to biological and sociocultural variables is recommended.
More Related Videos
Related Concept Videos
Disorders of the Female Reproductive System
Theoretical Approaches to Psychological Disorder
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Panic Disorder
Depressive Disorders: MDD and Dysthymia
Bipolar Disorder
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

