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Vascular manifestations of Behçet's disease. Eighteen cases among 140 patients

Aline Tohmé1, Noël Aoun, Bassam El-Rassi

  • 1Department of Internal Medicine, Hôtel-Dieu de France Hospital of Beirut, School of Medicine, Saint Joseph University of Beirut, rue Adib Ishaac, Beirut, Lebanon. atohme2@inco.com.lb

Joint Bone Spine
|October 18, 2003
PubMed

Insights

Vascular involvement in Behçet

Area of Science:

  • Rheumatology and Immunology
  • Vascular Medicine
  • Behçet's Disease Research

Background:

  • Behçet's disease (BD) is a multisystem inflammatory disorder.
  • Vascular involvement is a significant and potentially severe complication of BD.
  • Understanding the characteristics of vascular BD is crucial for effective management.

Observation:

  • A retrospective study identified 18 patients (13%) with vascular involvement among 140 BD patients.
  • Vascular manifestations were more frequent in men and occurred at a younger age.
  • Common vascular lesions included thrombophlebitis and arterial thromboses, with caval thrombosis and arterial occlusions being most serious.

Findings:

  • Thrombophlebitis was more prevalent in men, while arterial occlusions were more common in women.
  • Combined therapy with glucocorticoids, anticoagulants, and immunosuppressants showed efficacy.
  • Superior vena cava syndrome and extracranial arterial occlusion responded well to medical treatment.

Implications:

  • Vascular manifestations, especially venous lesions, are common in Behçet's disease in Lebanon.
  • Early recognition and appropriate treatment strategies are vital for managing vascular complications in BD.
  • Further research into optimal therapeutic regimens for diverse vascular BD presentations is warranted.
Abstract

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