Related Experiment Video
Updated: Aug 30, 2026

In vitro Transcription and Capping of Gaussia Luciferase mRNA Followed by HeLa Cell Transfection
Published on: March 26, 2012
Partial molar volumes of mRNA 5' cap analogues
Jedrzej Szymanski1, Janusz Stepinski, Jaroslaw Poznanski
1Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warszawa, Poland.
Abstract:
Partial molar volumes in aqueous solution of eleven selected 7-methylguanine cap-analogues and their guanine counterparts were determined by means of density measurements. Hydrophobicity of the investigated compounds regarding their structural features was analysed within the framework of the solute-solvent interaction model, based on the relative density of the molecular solvation shell.
Related Concept Videos
Nucleic Acid Structure
DNA Structure
DNA has a double-helix structure. The...
mRNA Stability and Gene Expression
Cis-acting Elements involved in mRNA stability
Regulated mRNA Transport
Ribosomal RNA Synthesis
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...
Nucleic Acids
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids
