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Covalent coupling of a PIM-1 oncogene targeted PNA with an antennapedia derived peptide

J R Bertrand1, N Sumbatyan, C Malvy

  • 1CNRS, UMR 8121, Institut Gustave Roussy, Villejuif cedex, France. irb@igr.fr

Nucleosides, Nucleotides & Nucleic Acids
|October 21, 2003
PubMed

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Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein.