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Safety and efficacy of influenza vaccine in children

Leslie G B Goldstein1

  • 1College of Pharmacy, Idaho State University, Pocatello, ID, USA. ELSAD@aol.com

The Annals of Pharmacotherapy
|October 21, 2003
PubMed

Insights

Influenza vaccines are safe and effective for children with asthma. This review addresses concerns about potential asthma exacerbations, confirming the benefits of immunization in this population.

Area of Science:

  • Pediatric Pulmonology
  • Vaccinology
  • Immunology

Background:

  • Influenza poses a significant health risk to children with asthma.
  • Concerns exist regarding the safety of influenza vaccination in asthmatic children, potentially leading to under-immunization.
  • Previous research has focused on the burden of influenza and vaccine safety in this vulnerable group.

Purpose of the Study:

  • To evaluate the safety and efficacy of influenza vaccines in pediatric asthma patients.
  • To address concerns about potential vaccine-induced asthma exacerbations.
  • To determine the benefits of influenza vaccination in asthmatic children, including those on glucocorticoid therapy.

Main Methods:

  • A comprehensive literature search was conducted using MEDLINE.
  • The search covered the period from 2002 to March 2003.
  • Key search terms included "asthma," "exacerbation," "children," "vaccine," and "influenza."

Main Results:

  • Studies investigated the impact of influenza on asthmatic children.
  • The safety profile of influenza vaccines in this population was assessed.
  • Efficacy and benefits, particularly in conjunction with glucocorticoid burst therapy, were examined.

Conclusions:

  • Influenza vaccines demonstrate a favorable safety profile in children with asthma.
  • The tested influenza vaccines are efficacious in asthmatic children.
  • Vaccination is recommended to mitigate influenza-related risks in this population.
Abstract

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