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Related Experiment Videos

Giant hydronephrosis mimicking progressive malignancy.

Andres Jan Schrader1, Georgia Anderer, Rolf von Knobloch

  • 1Department of Urology, Philipps-University Medical School, Baldingerstrasse, D-35043 Marburg, Germany. ajschrader@gmx.de

BMC Urology
|October 21, 2003
PubMed
Summary
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Giant hydronephrosis, a rare condition, can mimic malignant tumors. This case highlights the diagnostic challenges and the importance of considering hydronephrosis in abdominal masses.

Area of Science:

  • Nephrology
  • Urology
  • Radiology

Background:

  • Giant hydronephrosis is a rare condition, typically involving 1-2 liters of fluid.
  • This case presents a rare instance of giant hydronephrosis mimicking a malignant abdominal tumor.

Observation:

  • A 78-year-old woman presented with a large abdominal mass, initially suspected to be a malignant tumor.
  • CT scans revealed a giant cystic tumor filling the abdomen, with radiologists suspecting kidney and ovarian neoplasms.
  • Laparotomy exposed a large cystic structure (35x30x25 cm) and a pelvic mass, both resected.

Findings:

  • Histopathology confirmed a >15 kg giant hydronephrotic right kidney with minimal residual parenchyma.
  • A co-existing ovarian cyst with regressive changes was also identified.

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  • No evidence of malignant growth was found in either specimen.

    • Implications:

    • Giant hydronephrosis can be challenging to diagnose due to renal parenchyma atrophy.
    • Abdominal cystic masses necessitate considering hydronephrosis in differential diagnoses, even without other pathologies.
    • Combining imaging modalities and endourological techniques can improve diagnostic accuracy for giant hydronephrosis.