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Published on: September 23, 2022
[Fever and petechial exanthema in children]
J A Soult Rubio1, J Navarro González, P Olano Claret
1Servicio de Pediatría General, Hospital Infantil Universitario Virgen del Rocío, Sevilla.
Insights
Identifying severe pediatric infectious diseases requires careful monitoring. A child
Area of Science:
- Pediatric Infectious Diseases
- Clinical Pathology
Background:
- Fever and petechiae are common presenting symptoms in children.
- Distinguishing between mild and severe infectious diseases is clinically challenging.
Purpose of the Study:
- To identify clinical and analytical parameters predicting severe disease in children presenting with fever and petechiae.
- To assess the incidence of specific severe infections, such as meningococcal disease.
Main Methods:
- Retrospective study of 172 pediatric patients.
- Analysis of clinical presentation, white blood cell count, and coagulation studies.
- Evaluation of diagnostic accuracy for predicting severe outcomes.
Main Results:
- No single parameter reliably predicted all severe diseases.
- Deterioration in general clinical state, abnormal white cell counts, and coagulation abnormalities are critical warning signs.
- Normal clinical and analytical findings indicate a low risk of severe disease.
- Meningococcal disease was prevalent, accounting for 26% of cases.
Conclusions:
- A combination of clinical assessment and laboratory tests is crucial for early detection of serious pediatric infections.
- Prompt recognition of alert signals can guide timely intervention and improve patient outcomes.
- High incidence of meningococcal disease highlights the importance of considering this diagnosis in febrile children with petechiae.
Abstract:
In an attempt to determine clinical and analytical predictive parameters of a possible grave disease, we have carried out a retrospective study of 172 children admitted to our hospital with fever and petechiae as initial symptoms. The ages ranged between 1 month and 10 years. Even though we have not found a clinical symptom or analysis sufficiently sensitive as to predict all grave diseases, the general clinical state of the child associated with either a high or low white cell count and an abnormal coagulation study should be alert signals for a serious infectious disease. On the contrary, if the clinical and analytical parameters are within normal limits the risk of a grave disease is low. We emphasize the high incidence of meningococcal disease (26%).
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