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Published on: July 1, 2015
[Biologic rhythm of respiratory rate in the first trimester of life]
J Ardura Fernández1, J M Andrés de Llano, J Aldana Gómez
1Departamento de Pediatría, Escuela Superior de Arquitectura, Universidad de Valladolid.
Insights
Newborn and infant respiratory rates show developing circadian and ultradian rhythms, influenced by environmental factors. This maturation highlights the importance of time series analysis for physiological evaluation.
Area of Science:
- Chronobiology
- Pediatric Physiology
- Infant Development
Context:
- Respiratory rate variability in newborns and infants is not fully understood.
- The influence of environmental factors on infant physiological rhythms requires further investigation.
- Maturation of biological rhythms in early life is a critical developmental process.
Purpose:
- To record and analyze respiratory rate rhythms in newborns and infants.
- To investigate the maturation process of these respiratory rhythms.
- To determine the impact of environmental factors (light, noise, temperature) on infant respiratory patterns.
Summary:
- Respiratory rate was monitored in infants aged 1 day to 90 days.
- Rhythmometric analysis revealed significant circadian rhythm differences in older infants (60 and 90 days).
- An ultradian rhythm (3-hour cycle) emerged in 30 and 90-day-old infants, suggesting developmental maturation.
Impact:
- The study identifies specific age-related changes in infant respiratory rhythms.
- Findings emphasize the role of environmental factors in shaping infant physiological patterns.
- This research underscores the necessity of considering time series data for accurate physiological assessment in infants.
Abstract:
This study was designed to address the following objectives: 1) To record the respiratory rate in a population of newborns and infants. 2) To verify the existence of a rhythm in each population group, as well as the organization and maturing process of these rhythms. 3) To determine the possible influence of environmental factors on these rhythms. The study population consisted of the following groups and ages: A) 1 day (21 cases); B) 7 (15 cases); C) 15 (10 cases); D) 30 (17 cases); E) 60 (17 cases); F) 90 (18 cases). Respiratory rate was continuously monitored and recorded, as well as environmental light, noise and temperature. Rhythmometric analysis of the data was done by simple Cosinor test and analysis of variance. The zero amplitude test showed statistically significant differences in the circadian rhythm of groups E and F (p < 0.005). An ultradian rhythm of 3 hours was detected in groups D and F. Environmental factors also showed a circadian rhythm. The appearance of an ultradian rhythm suggest the maturation in a rhythm. To evaluate physiological parameters, reference to time series must be considered.
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