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Published on: September 22, 2023
Dietary and socio-economic factors associated with beriberi in breastfed Lao infants
Douangdao Soukaloun1, Sengchanh Kounnavong, Bounthom Pengdy
1Department of Pediatrics, Mahosot Hospital, Vientiane, Lao PDR.
Insights
Infant beriberi in Lao PDR is linked to maternal diet and socioeconomic status. Rice preparation methods and limited food diversity in mothers significantly increase infant risk.
Area of Science:
- Nutrition
- Pediatrics
- Public Health
Background:
- Beriberi, a disease caused by thiamine (vitamin B1) deficiency, can affect infants.
- Infantile beriberi presents as congestive heart failure or shock, particularly in breastfed infants.
- Understanding risk factors is crucial for prevention and early intervention in affected populations.
Purpose of the Study:
- To identify dietary and socio-economic factors associated with beriberi in infants in Vientiane, Lao PDR.
- To compare these factors between infants diagnosed with beriberi and healthy controls.
- To inform public health strategies for preventing infantile beriberi.
Main Methods:
- A case-control study design was employed.
- Forty-three breastfed infants diagnosed with beriberi were matched with 43 healthy, breastfed control infants.
- Data on maternal diet, rice preparation, education, income, occupation, and marital status were collected and compared.
Main Results:
- Mothers of infants with beriberi exhibited significantly less dietary diversity.
- Specific rice preparation methods, such as prolonged soaking of glutinous rice or discarding water from non-glutinous rice, were more common.
- Maternal factors included fewer years of schooling, inadequate income, hard physical labor, and being married to farmers.
Conclusions:
- Infantile beriberi in Lao PDR is strongly associated with maternal dietary practices, particularly rice preparation methods.
- Socio-economic status, including education and income, plays a significant role in the incidence of beriberi.
- Targeted nutritional education and socioeconomic support for lactating mothers are essential for preventing thiamine deficiency in infants.
Abstract:
A case-control study was conducted to investigate the dietary and socio-economic factors associated with beriberi in infants attending three public hospitals in Vientiane, Lao PDR. Forty-three breast-feeding infants with a median (range) age of 3 (1-9) months were admitted with beriberi. This was defined as the presence of signs of congestive heart failure or shock in the absence of fever or other signs of sepsis, hypovolaemia or cardiac abnormalities, with rapid clinical improvement following parenteral thiamine. Subjects were matched by age and diet to 43 breast-feeding healthy control infants. Compared with control mothers, mothers of infants with beriberi had significantly less diet diversity (p <0.001), soaked glutinous rice for significantly longer or were more likely to pour off excess water from non-glutinous rice (p =0.006), had fewer years of schooling (p <0.05), were more likely to report that income was inadequate for basic needs (p <0.001), to perform hard physical labour (p <0.01) and to be married to farmers (p <0.01). Clinically significant thiamine deficiency in breastfed infants in Lao relates to methods of preparing rice, the food selected by lactating mothers and the family's socio-economic status.
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