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Selective association of cholesterol with long-chain phospholipids in liquid-ordered bilayers: support for the
Michihiro Sugahara1, Maki Uragami, Steven L Regen
1Department of Chemistry, Lehigh University, Bethlehem, PA 18015, USA.
Abstract:
Nearest-neighbor recognition experiments, which have been carried out under fluidizing and condensing conditions, using exchangeable dimers derived from 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine, and cholesterol, have provided strong evidence that sterol-phospholipid recognition is limited to the liquid-ordered phase.
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