Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Neuronavigator-guided glioma surgery.

Guhong Du¹, Liangfu Zhou, Ying Mao

¹Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai Neurosurgical Center, Shanghai 200040, China. dghong@online.sh.cn

Chinese Medical Journal

|October 23, 2003

Summary

Neuronavigator-guided surgery for gliomas shows promise, but intraoperative brain shifts can affect accuracy. A "micro-catheter fence post" technique helps compensate for these shifts, improving tumor removal rates and reducing complications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Green extraction of non-starch polysaccharides from millet using a deep eutectic solvent: structural elucidation and structure-activity relationship of their inhibition of α-glucosidase.

Food chemistry·2026

Same author

Metabolic Modulation of Type 2 Diabetes Mellitus by 1-Deoxynojirimycin: A Multifaceted Approach.

Antioxidants (Basel, Switzerland)·2026

Same author

Molecular and clinical characteristics of glioma patients with germline pathogenic mutations of Lynch syndrome genes: a large-scale multicenter study.

Journal of translational medicine·2026

Same author

Bioactivity and prebiotic potential of insoluble dietary fiber from discarded Chinese cabbage outer leaves and the metabolomic dynamics of bound polyphenols during alkaline extraction, in vitro gastrointestinal digestion and colonic fermentation.

Food research international (Ottawa, Ont.)·2026

Same author

Detection of the characteristic magnetic signal of paclitaxel and its application in the inhibition of glioma cells.

Fundamental research·2026

Same author

iTRAQ-Based Proteomics Reveals the Potential Mechanisms Underlying Diet Supplementation with Stevia Isochlorogenic Acid That Alleviates Immunosuppression in Cyclophosphamide-Treated Broilers.

Animals : an open access journal from MDPI·2026

Area of Science:

Neurosurgery
Oncology
Medical Technology

Background:

Gliomas pose significant surgical challenges due to their location and potential for brain shift.
Neuronavigation systems aim to improve surgical precision but can be affected by intraoperative anatomical changes.

Purpose of the Study:

To evaluate the effectiveness of neuronavigator-guided surgery for glioma resection.
To assess the impact of intraoperative brain shifts on surgical accuracy.
To investigate the utility of the "micro-catheter fence post" technique in mitigating brain shift effects.

Main Methods:

Eighty patients with gliomas underwent surgery using the StealthStation neuronavigator.
Brain shifts were measured at the dura, cortical surface, and lesion margin in 27 cases.

Related Experiment Videos

The "micro-catheter fence post" technique was employed to compensate for brain shifts in superficial gliomas.

Main Results:

Mean fiducial error was 2.03 mm, with predicted accuracy of 2.43 mm.
Intraoperative brain shifts ranged from 3.44 mm to 7.58 mm.
Total tumor removal was achieved in 82.7% of cases, with improved or unchanged neurological symptoms in 85.0%.

Conclusions:

Intraoperative brain shifts are a primary cause of spatial inaccuracy in neuronavigator-guided glioma surgery.
The "micro-catheter fence post" technique effectively compensates for brain shifts.
This technique enhances total tumor resection rates and decreases surgical complications.