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Dysphagia associated with risperidone therapy.

Jonathan T Stewart1

  • 1Department of Psychiatry, University of South Florida College of Medicine, Tampa, Florida, USA. jstewa22@tampabay.rr.com

Dysphagia
|October 23, 2003
PubMed
Summary
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Atypical neuroleptic medications like risperidone can cause dysphagia (difficulty swallowing). This dangerous side effect is reversible upon medication withdrawal, highlighting the need for clinical awareness.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Gastroenterology

Background:

  • Neuroleptic agents are used to manage psychosis.
  • Atypical neuroleptics are presumed to have fewer neurological side effects than older agents.
  • Dysphagia is a known, though infrequent, adverse effect of neuroleptic treatment.

Observation:

  • A 76-year-old male patient developed dysphagia.
  • The patient was being treated with risperidone, an atypical neuroleptic.
  • Dysphagia was confirmed radiographically.

Findings:

  • The patient's dysphagia resolved after discontinuation of risperidone.
  • This suggests a causal link between risperidone and the onset of dysphagia.
  • The adverse effect was highly reversible.

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Implications:

  • Clinicians must consider dysphagia as a potential side effect of risperidone.
  • Early recognition and withdrawal of the neuroleptic can reverse dysphagia.
  • This case underscores the importance of monitoring for neurological side effects even with atypical antipsychotics.