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Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
Published on: June 20, 2014
[Cardiac effects of dermatomyositis. A case report]
F J Cuilleret1, B Agraou, X Kyndt
1Centre hospitalier, service de cardiologie et des soins intensifs, 59322 Valenciennes.
Dermatomyositis can cause serious heart problems like ventricular tachycardia and cardiomyopathy, often missed clinically but common at autopsy. While some cardiac issues respond to treatment, others like dilated cardiomyopathy may persist.
Area of Science:
- Cardiology
- Rheumatology
- Neurology
Background:
- Dermatomyositis and polymyositis are inflammatory myopathies with known cardiac involvement.
- Cardiac manifestations are often subclinical, discovered incidentally at autopsy.
- Understanding these cardiac effects is crucial for comprehensive patient management.
Observation:
- A case of dermatomyositis presenting with prominent cardiac anomalies is described.
- The patient exhibited ventricular tachycardia and dilated hypokinetic cardiomyopathy.
- Electrocardiographic findings included frequent conduction disturbances.
Findings:
- Ventricular tachycardia was responsive to therapeutic intervention.
- The associated dilated cardiomyopathy proved resistant to treatment.
- Cardiac insufficiency could often be stabilized with appropriate medical management.
Implications:
- Highlights the importance of cardiac monitoring in patients with dermatomyositis.
- Suggests a potential disconnect between clinical presentation and autopsy findings of cardiac disease.
- Emphasizes the need for tailored treatment strategies for different cardiac manifestations in inflammatory myopathies.
Related Concept Videos
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management
Myocarditis IV: Nursing Management
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Cardiomyopathy II: Dilated Cardiomyopathy

