Related Experiment Video

Updated: Aug 30, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

[Cardiobacterium hominis endocarditis. A case report]

E Balcou-Leroy1, J Bera, A S Fugére

  • 1Service de médecine polyvalente, centre hospitalier de Dunkerque, avenue Louis Herbeaux, 59240 Dunkerque.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|October 24, 2003
PubMed

Insights

Cardiobacterium hominis endocarditis can cause severe heart failure and requires prompt surgical intervention. Advanced diagnostic methods like Polymerase Chain Reaction improve the identification of this difficult-to-culture bacterium.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Cardiobacterium hominis, a member of the fastidious HACEK group, is an infrequent cause of bacterial endocarditis.
  • Endocarditis due to C. hominis often presents with significant valvular damage and potential hemodynamic compromise.

Observation:

  • This case highlights acute mitral insufficiency and left heart failure secondary to C. hominis endocarditis.
  • The patient underwent successful surgical valvuloplasty for rapid clinical improvement.
  • Literature review of 71 cases indicates a predominantly subacute presentation with frequent thromboembolic and hemodynamic complications.

Findings:

  • Bacteriological diagnosis of C. hominis is challenging due to slow growth and specific culture requirements.
  • Polymerase Chain Reaction (PCR) offers a promising, effective method for identifying fastidious organisms like C. hominis.
  • Large, friable vegetations contribute to the high pathogenicity and complication rate.

Implications:

  • Early diagnosis and intervention, including surgery, are crucial for managing C. hominis endocarditis.
  • Molecular diagnostic techniques like PCR are vital for improving the detection of rare bacterial pathogens.
  • Understanding the clinical and microbiological features of C. hominis endocarditis informs treatment strategies and patient outcomes.

More Related Videos

Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes09:18

Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes

Published on: May 27, 2015

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...