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Updated: Aug 30, 2026

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
Alternative treatment for gallbladder stones in portal venous thrombosis
Sonia Penteado1, Marcel C Machado, José Eduardo M Cunha
1Gastrointestinal Surgery, Division of Biliopancreatic Surgery, University of S. Paulo Medical School, S. Paulo, Brazil. viasbiliares.pancreas@hcnet.usp.br
Insights
Cholecysto-jejunostomy offers a safe alternative for treating gallbladder stones in patients with portal vein thrombosis, avoiding hazardous dissection and complications.
Area of Science:
- Gastroenterology and Hepatology
- Surgical Innovation
- Vascular Surgery
Background:
- Gallbladder stone treatment via cholecystectomy is risky in patients with portal vein thrombosis due to potential bleeding from collateral vessels.
- Dissection in these cases can lead to significant hemorrhage and coagulation issues.
Purpose of the Study:
- To evaluate the safety and efficacy of cholecysto-jejunostomy as an alternative surgical approach.
- To manage symptomatic gallbladder stones in patients with coexisting portal vein thrombosis.
Main Methods:
- Cholecysto-jejunostomy was performed in three patients with symptomatic gallbladder stones and portal vein thrombosis.
- This technique aimed to bypass the need for dissection in hazardous areas.
Main Results:
- The surgical procedure was uneventful, with no requirement for blood or plasma transfusions.
- Patients showed stable hematocrit and liver function tests, with no postoperative complications.
- The procedure was well-tolerated, with discharge between days 5-7 and no biliary complications during 2-3 years of follow-up.
Conclusions:
- Cholecysto-jejunostomy is a safe and effective treatment for symptomatic gallbladder stones in patients with portal vein thrombosis.
- This method provides a viable alternative to conventional cholecystectomy in high-risk patients.
Background/Aims:
Cholecystectomy for treatment of gallbladder stones in patients with portal vein thrombosis can be a hazardous procedure. Dissection into an area of thin-walled collateral vessels can trigger troublesome bleeding and consequent blood coagulation disorders.
Methodology:
In order to avoid dissection, cholecysto-jejunostomy was used as the treatment of choice in three patients with symptomatic gallbladder stones and portal vein thrombosis.
Results:
Surgical procedure was uneventful, blood or plasma transfusions were not required either at surgery or afterwards. Pre- and postoperative hematocrit evaluations showed no difference, as well as liver function tests. The procedure was well tolerated and patients were discharged from day 5 to 7. Follow-up ranged from 2 to 3 years, no biliary complications were found during this period.
Conclusions:
Choleysto-jejunostomy is a safe procedure and can be used as an effective treatment of symptomatic gallbladder stones in patients with portal vein thrombosis.
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