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Diagnosis and management of hereditary angioedema: an American approach

Bruce L Zuraw1

  • 1Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10666 N. Torrey Pines Road, La Jolla, CA 92037, USA. zuraw@scripps.edu

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|October 24, 2003
PubMed

Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of angioedema, and caused by a deficiency of the plasma protein C1 inhibitor. HAE attacks carry a substantial risk of morbidity or even mortality, making it imperative that the correct diagnosis be established and an appropriate management plan be in place. This report reviews the current diagnostic and therapeutic approaches available in the United States. Areas in which the diagnostic or therapeutic tools are deficient are discussed, and the prospects for improved therapeutic modalities highlighted.

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