Is it jolly SAD?
Related Experiment Video
Updated: Aug 9, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
Published on: March 2, 2015
1Department of Chemistry, University of York, Heslington, York YO10 5DD, England. e.dodson@ysbl.york.ac.uk
Abstract:
Examples of phasing macromolecular crystal structures based on single-wavelength anomalous dispersion (SAD) have demonstrated that this approach may have general applications in structural biology. With better data-collection facilities and cryogenic techniques, combined with powerful data-processing, phasing and density-modification programs, the SAD approach may prove simpler than phasing from multi-wavelength (MAD) measurements. It can be performed at any wavelength where anomalous scattering can be observed, in many cases using laboratory X-ray sources. However, there is still a need for accurate data, successful phase improvement and a certain amount of luck. This paper extends the discussion of Jolly SAD in Dauter et al. [Dauter, Z., Dauter, M. & Dodson, E. (2002), Acta Cryst. D58, 494-506].
Related Concept Videos
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...
Fatigue
Retarders
The function of retarders is to delay the setting of concrete, and this effect can be measured using a penetration test. The retardation process involves adding...
Emotional Expression
Universal Facial Expressions
Psychologist Paul Ekman identified seven basic...
Jaundice

