Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Methodological and statistical considerations in measuring alcohol treatment effects.

Robert L Stout1

  • 1Decision Sciences Institute, Providence, Rhode Island 02906, USA. stout@pire.org

Alcoholism, Clinical and Experimental Research
|October 24, 2003
PubMed
Summary

Selecting outcome measures for treatment research requires balancing statistical power with social utility. Tailored, time-sensitive methods enhance power, but broader societal impact necessitates linking short-term outcomes to long-term benefits.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Brief Intervention Versus More Extensive Treatment for Alcohol Use Disorder (AUD): Testing the Comparability Hypothesis.

Journal of studies on alcohol and drugs·2026
Same author

Perspectives on a Technology-Based Smoking Cessation Intervention Among Youth Exiting Foster Care.

Children and youth services review·2025
Same author

School-Based Health Centers Addressing Health Equity for LGBTQ + Patients (SBHCs HELP): protocol for a stepped-wedge trial to implement innovations promoting structural competency.

BMC health services research·2024
Same author

Technology-Based Smoking Cessation for Youth Exiting Foster Care: A Pilot Randomized Trial.

Journal of public child welfare·2023
Same author

FRAMES Elements Associated With Alcohol Treatment Research Assessments and Related Behavior Change.

Journal of studies on alcohol and drugs·2023
Same author

Prevalence of Antibodies to COVID-19 Due to Infection or Vaccination in US Adults.

Journal of insurance medicine (New York, N.Y.)·2023

Area of Science:

  • Statistics in clinical research
  • Methodology in behavioral science

Background:

  • Treatment research design faces challenges in selecting appropriate outcome measures.
  • Key statistical and methodological considerations include statistical power and social utility.

Purpose of the Study:

  • To provide a statistical perspective on designing and selecting outcome measures for treatment research.
  • To explore the interplay between statistical power and social utility in outcome measurement.
  • To advocate for time-sensitive procedures and a series of studies linking short-term to long-term outcomes.

Main Methods:

  • Discussion of statistical power as a paramount issue in research design.
  • Emphasis on tailoring measures to predicted treatment effects and considering time-varying effects.

Related Experiment Videos

  • Illustration using advanced statistical methods to analyze the relationship between drinking and self-reported stress.

    • Main Results:

    • No single outcome measure is suitable for all treatment research due to varying treatment effects.
    • Time-sensitive procedures offer advantages for measuring specific treatment components and time-varying effects.
    • Advanced statistical analysis can reveal process data on treatment effects on responses to stressors.

    Conclusions:

    • Balancing statistical power with social utility is crucial for meaningful treatment research.
    • Future research should link specific short-term outcomes to broader, long-term societal benefits.
    • A series of studies is needed to bridge the gap between measurable outcomes and societal value.