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[Clinical analysis of aseptic meningitis caused by echovirus 13]

Seiya Kashiyama1, Michiko Fujitaka

  • 1Department of Clinical Laboratory, Saiseikai Hiroshima Hospital.

Kansenshogaku Zasshi. the Journal of the Japanese Association for Infectious Diseases
|October 25, 2003
PubMed

Insights

This study on echovirus 13 aseptic meningitis in children found typical symptoms like fever and headache. Cerebrospinal fluid analysis revealed initial polynuclear cell predominance, shifting to mononuclear cells during recovery.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Virology

Context:

  • Aseptic meningitis is a significant concern in pediatric populations.
  • Echovirus infections are a common cause of viral meningitis.
  • Understanding the clinical and laboratory features of echovirus 13 meningitis is crucial for diagnosis and management.

Purpose:

  • To describe the clinical symptoms and laboratory findings in children diagnosed with echovirus 13 aseptic meningitis.
  • To analyze cerebrospinal fluid (CSF) cell counts and biochemical markers during the acute and recovery phases.
  • To compare findings with previous reports of echovirus aseptic meningitis.

Summary:

  • Twenty-one pediatric patients with echovirus 13 aseptic meningitis presented with fever and headache; some experienced vomiting.
  • Early CSF analysis showed polynuclear cell predominance (mean WBC 8,283/microliter, mean CRP 0.8 mg/dl), which shifted to mononuclear predominance during recovery.
  • One case presented with atypical symptoms including restlessness and elevated CRP (6.2 mg/dl), highlighting the need for careful diagnosis.

Impact:

  • Provides detailed clinical and laboratory data for echovirus 13 aseptic meningitis in children.
  • Contributes to the differential diagnosis of viral meningitis in pediatric patients.
  • Reinforces the generally mild nature of echovirus meningitis while noting potential diagnostic challenges in atypical cases.

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