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Updated: Aug 30, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
[Bone metabolism in adolescent girls with short course of anorexia nervosa]
Ewa Serafinowicz1, Renata Wasikowa, Zdzisława Iwanicka
1Katedra i Klinka Endokrynologii Wieku Rozwojowego AM we Wrocławiu, Wrocław, Poland.
Objective:
The objective of this study was to determine the prevalence of bone mass reduction and determine its causes in young girls with short course of anorexia nervosa (AN).
Method:
Bone mineral density (BMD)of lumber spine by dual energy x-ray absorptiometry, total alkaline phosphatase (TAP), bone-Gla protein (BGP), urine deoxypyridinoline (DPYR), DPYR, urine calcium, sex hormones were measured in 24 in-patient girls with diagnosed AN and 20 healthy volunteers.
Results:
Girls with AN had a significantly lower BMD than their age-matched controls. Osteopenia and osteoporosis were present even in the group with AN diagnosed within the previous 12 months. BMD correlated negatively with minimal BMI and positively with the duration of regular menses before AN onset. BGP and DPYR were significantly lower in AN patient than in the control group. Values of urine calcium of AN patients were comparable with control group, but showed a positive correlation with disease duration.
Discussion:
Reduction of bone mineral density is present in girls with short course of AN. Nutritional status is the most important predictor of BMD. Bone metabolism is decreased in the early stages of the disease.
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