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CT and MR findings of brain aspergillosis

Takashi Okafuji1, Hidetake Yabuuchi, Yoshihisa Nagatoshi

  • 1Department of Radiology, National Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka 811-1395, Japan. oka-pu@radiol.med.kyushu-u.ac.jp

Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society
|October 25, 2003
PubMed

Insights

Brain aspergillosis presents as multiple lesions in the corticomedullary junction on CT and MR imaging. Histopathology confirms these lesions are hemorrhagic infarcts caused by invasive Aspergillus.

Area of Science:

  • Neurology
  • Radiology
  • Pathology

Background:

  • Brain aspergillosis is a rare but serious fungal infection.
  • Accurate diagnosis relies on correlating imaging findings with histopathology.

Observation:

  • Multiple lesions were observed in the corticomedullary junction (CMJ) on CT and MR imaging.
  • These lesions disrupted cortical sulci and showed atypical contrast enhancement patterns.

Findings:

  • Imaging revealed central enhancing structures continuous with dilated, enhanced cortical vessels.
  • Histopathology confirmed hemorrhagic infarcts in the CMJ with thrombosed vessels due to Aspergillus hyphae.

Implications:

  • This case highlights characteristic imaging findings of brain aspergillosis.
  • Early recognition of these patterns can aid in timely diagnosis and treatment of invasive fungal infections.

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